Hyper-CVAD regimen for NHL and ALL: Part A: Cyclophosphamide, Vincristine, Doxorubicin, Dexamethasone. Contact Physician. HYPERCVAD Regimen. Cyclophosphamide-Vincristine-Doxorubicin- Dexamethasone-Methotrexate-Leucovorin-. Cytarabine. Disease Site. Modification of the hyper-CVAD regimen with anthracycline intensification did not improve outcome. Other modifications of the program could include.
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A variety of antiemetic drugs may be used, including granisetronondansetronmetoclopramide and cyclizine. If you are worried about gaining weight, talk to your doctor or nurse. Blood clot risk Cancer and some cancer treatments can increase the risk of a blood clot. Hyper-CVAD may affect your skin.
You will have blood tests to check how well your liver is working.
Order booklets or audio CDs about chemotherapy. After your treatment is over, most side effects start to improve. You may suddenly feel warm and your face may get red while the doxorubicin is being given. There are some rare side effects that are not listed. If you think you need dental treatment, talk to your cancer doctor or nurse.
A company limited by protocok, registered in England and Wales company number This releases uric acid a waste product into the blood. Hyper-CVAD is usually given into a vein and as tablets. Tell others about your experiences and get answers to your questions. Your doctor will talk to you about how to manage this. Contact the hospital straight away if: If you feel unwell or have any of these signs, tell them straight away.
They sometimes need to lower the dose of the drug or delay treatment for a short time. Your nurse will check your blood regularly for this. Hyper-CVAD is a chemotherapy regimen used to treat some forms of leukemianon-Hodgkin lymphoma high grade and lymphoblastic lymphoma Contents. You can also watch tutorials on wigs, headwear and eye make up. The regimen is usually administered on an in-patient basis, using a continuous venous access device such huper a peripherally inserted central catheter PICCa protockl line or a port-a-cath.
You will have blood tests to check how well your kidneys are working.
Your nurse can talk to you about ways to cope with hair loss. The protocol was originally developed to treat leukemia in young, fit patients, due to its intensity, but has since begun to be used more widely.
You will have each schedule four times in a pattern of A then B. You will be given fluids through a drip before and after cyclophosphamide.
The swelling gets better after the treatment ends.
The majority of patients will experience a degree of pancytopeniaincluding anaemiathrombocytopeniaand leukopeniadue ccvad the myelosuppressive effect of chemotherapy. These may be done before, during, and sometimes after treatment. You will have a blood test before having more chemotherapy. This is called extravasation. Hyper-CVAD can cause a rash, which may be itchy. Wear gloves to protect your nails when you are doing things in the house or garden.
Tummy pain or indigestion Steroids can irritate the stomach lining. You also start taking dexamethasone tablets for four days days 11 to Signs of a reaction can include:. Methotrexate is given as a drip over 24 hours. There are serious side effects and complications arising from the administration of the various agents, which require careful management in an appropriate health-care setting. The side effects of intrathecal hyper-CVAD may be different from those mentioned protlcol.
Your appetite will go back to normal when you stop taking them. The symptoms usually improve slowly after treatment finishes, but for some people they may never go away. It is also important to empty your bladder regularly and to try to pass urine as soon as you feel the need to go. Sometimes cvar and cytarabine are given by injection into the fluid around the spinal cord intrathecally. If the number hypsr red blood cells is low, you may be tired and breathless. Blog post What surprised you about chemotherapy?
Hyper-CVAD chemotherapy – Macmillan Cancer Support
Tell your doctor or nurse straight away if you notice any of these symptoms. The aim is to administer as many cycles as possible or necessary protoco, as short a time as possible.
You can use our checklists for home, work and travel to help you get organised.
There are things you can do to look after your nails:. If you have pain or notice any change in your vision, always tell your doctor or nurse. Each cycle of hyper-CVAD hyepr 21 days. A low white blood cell count is called neutropenia. Timing of cycles will be somewhat dependent on the patient’s recovery from the last cycle.
Chemotherapy can reduce the number of platelets in your blood. Tell your doctor or nurse straight away cva you:.